EnGagE Worshop – Principles of Psychiatric Genetic Counselling and Testing

April 11th – 12th 2019

Comité d’organisation : Dr Boris Chaumette, Pr David Cohen, Pr Marie-Odile Krebs, Dr Claudine Laurent-Levinson, Pr Franziska Degenhardt (Chair of EnGagE)

Remerciements à :

Revoir les moments forts de la journée

Jeudi 11 avril 2019

Introduction (MO. Krebs)

9h00

• Welcome introduction (MO. Krebs)

• Welcome introduction (F. Degenhardt)

9h30

• Presentation of the French initiatives: Reference Center for Rare Psychiatric Diseases and DefiScience network (D. Cohen)

10h00

• The genetic architecture of autism from risk to resilience (T. Bourgeron)

Session Psychiatric Disorders (D. Cohen)

11h00

• Introduction to psychiatric disorders (B. Chaumette)

11h30

• Clinical neurogenetics of psychiatric disorders (A. Poisson)

12h00

• Clinical red flags for organicity in schizophrenia (O. Bonnot)

12h30

• Medical and genetic risk factors in early-onset psychosis (C. Laurent-Levinson)

Session Genetic Counselling (F. Degenhardt)

14h30

• Clinical and personal utility of genetic diagnoses in individuals with neuropsychiatric disorders (B. Finucane)

Future of Genetics (F. Degenhardt/MO. Krebs)

16h30

• Artificial intelligence for facial images: is there a characteristic gestalt in schizophrenia? (P. Krawitz)

17h30

• Recent and future developments in medical genetics (S. Lyonnet)

Vendredi 12 avril 2019

Session Genetic Testing (K. Tammimies)

9h00

• Short introduction to genetic testing with focus on chromosomal microarray (K. Tammimies)

9h45

• Medical consequences of pathogenic CNVs among carriers in the UK biobank (G. Kirov)

Illustration of Testing and Counselling in Psychiatry (B. Chaumette)

11h00

• 22q11.2 deletion syndrome and the clinical application of genetic testing and genetic counselling for major psychiatric illness
  (A. Bassett)

12h00

• Modelling the effect-size of rare variants, genome-wide, on cognitive and behavioural traits (S. Jacquemont)

Session Patient Perspectives (D. Levinson)

14h00

• New therapeutic advances in Prader-Willi syndrome (M. Tauber)

14h30

• Unique: Supporting & informing families and professionals challenged by rare chromosome & genome disorders (B. Searle)